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Adenovirus, Definition, Symptoms, Causes, Diagnosis, Treatment, Prevention, Complications

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Adenovirus, Definition, Symptoms, Causes, Diagnosis, Treatment, Prevention, Complications

Adenoviruses are a group of viruses that cause infections of the respiratory tract, eyes, lungs, and digestive tract. This disease can affect anyone, but more often affects infants and toddlers. In most cases, the adenovirus causes a mild infection. However, adenovirus can also cause serious infections, especially if it occurs in people who have weak immune systems.

Currently, adenovirus is suspected as the cause of mysterious acute hepatitis. Mysterious acute hepatitis itself is hepatitis that attacks children under 16 years of age. According to the study, adenovirus was detected in 72% of the 126 patients who had undergone the examination.

Causes of Adenovirus 

There are about more than 100 types of adenoviruses. Of these, about 49 types can infect humans.
Adenovirus can cause infections in various parts of the body, such as the respiratory tract, digestive tract, and eyes. Some infectious diseases that occur due to adenovirus are: Cough and cold

  • Croup
  • Conjunctivitis
  • Bronchitis
  • Pneumonia
  • Gastroenteritis
  • Urinary tract infection (UTI)
  • Gastrointestinal infections
  • Meningitis

Adenoviruses are highly contagious. This virus can spread in several ways, namely:

  • Inhaling droplets of saliva from patients with adenovirus infection when sneezing or coughing
  • Touching objects that have been contaminated with the virus, then touching your nose, mouth, or eyes without washing your hands
  • Touching feces with an adenovirus infection, for example when changing diapers

Adenovirus risk factors

Adenovirus can attack anyone. However, there are several factors that increase a person's risk of developing adenovirus, namely: Under 5 years old (toddlers)

  • Have a weak immune system, for example because you are suffering from HIV/AIDS
  • Recently had an organ transplant
  • Living or living in a crowded, slum, and poor sanitation environment

Symptoms of Adenovirus

Symptoms of adenovirus infection generally appear 2–14 days after a person is exposed to the virus. Symptoms that appear can vary, depending on the type of adenovirus and the disease caused by the virus, including:

1. Symptoms of a cold cough:

  • Fever
  • Cough
  • Sore throat
  • Weak
  • Runny nose or stuffy nose
  • Headache
  • Muscle ache
  • Hard to breathe

2. Symptoms of bronchitis and pneumonia:

  • Cough with phlegm
  • Weak
  • Hard to breathe
  • Mild fever and chills
  • Chest discomfort

3. Symptoms of infection in the digestive tract:

  • Nausea and vomiting
  • Stomach cramps
  • Diarrhea

4. Symptoms of eye infection (conjunctivitis):

  • Redness of the eyes
  • Pain and feeling stuck in the eye
  • Sensitive to light
  • Corneal opacities
  • Visual impairment

Meanwhile, in patients with mysterious acute hepatitis, the initial symptoms that may arise are nausea, vomiting, severe diarrhea, and low-grade fever. If the condition worsens, the patient may also experience further symptoms such as:

  • Darker colored or concentrated urine like tea
  • Yellowing eyes and skin
  • Pale stools
  • Seizures
  • Loss of consciousness

When to go to the doctor


See a doctor immediately if you or your child experience symptoms of an adenovirus infection that get worse, such as:

  • Respiratory disorders
  • Swelling in the eye area
  • Fever that does not go down in a few days
  • Signs of dehydration, such as dry mouth and decreased urination


Because adenovirus is currently suspected as the cause of mysterious acute hepatitis, take your child to the doctor immediately if you experience early symptoms of the disease. Mysterious acute hepatitis can get worse and cause advanced symptoms. Therefore, do not delay taking your child to the doctor so that it can be treated immediately.

If your child has decreased consciousness, immediately take him to the ER for help.

Adenovirus Diagnosis


To diagnose adenovirus, the doctor will ask questions about the patient's symptoms and medical history. After that, the doctor will perform a thorough physical examination. To further confirm the diagnosis, the doctor will perform several supporting examinations, namely:

  • Blood and urine tests, to detect the presence of adenovirus by taking blood and urine samples
  • Stool examination, to determine the presence of adenovirus in feces
  • Antigen test, to detect proteins on the outside (antigen) of the adenovirus
  • PCR test, to detect the presence of adenovirus in the body through examination of samples of nasal mucus, throat, stool, or blood
  • Chest X-ray, to see the condition of the heart and lungs more clearly


To diagnose a mysterious acute hepatitis, doctors can perform a hepatitis virus serology test, to detect the hepatitis A–E virus type.

Adenovirus Treatment


Generally, adenovirus only causes infections that are classified as mild and do not require special treatment. Treatment aims to relieve symptoms and prevent possible complications.
Some of the treatment methods are:

Self care at home

In most cases, adenovirus can be treated with some self-care at home, such as:

  • Get enough rest
  • Drink lots of water
  • Consuming a nutritionally complete and balanced diet
  • Using nasal spray (nasal rinse)
  • Using a humidifier (humidifier)
  • Using moisturizer in the nose and mouth area


Treatment by doctor

Although generally cause infections that are classified as mild, adenovirus can also cause severe infections. In this case, the doctor can perform several treatments, such as:

  • Giving fluid infusion, to meet the needs of fluid intake
  • Administration of fever medicine, such as paracetamol, to treat fever
  • Administration of supplemental oxygen, such as a nasal tube or oxygen mask, to assist breathing
  • Administration of antiviral drugs, such as ribavirin and cidofovir, to inhibit the development of the virus, especially in immunocompromised patients


Adenovirus Complications

If left untreated, adenovirus infection can cause several complications, namely:

  • Chronic lung disease
  • Severe infection
  • Intussusception
  • Bronchiectasis


Patients with weak immune systems or have recently undergone organ transplants can also experience more severe complications. While in mysterious acute hepatitis, complications that can occur are liver damage to death.

Adenovirus Prevention

There are several ways that can be done to prevent adenovirus infection, namely:

  • Wash hands with soap and running water regularly. If there is no water, use a hand sanitizer that contains alcohol.
  • Avoid touching your eyes, nose, or mouth before washing your hands.
  • Avoid direct contact with people who are sick.
  • Eat healthy and nutritionally balanced foods, and make sure the food is clean and cooked.
  • Wash fruit and vegetables thoroughly before processing or eating.


If you experience symptoms similar to those of an adenovirus infection, take the following steps to avoid spreading it to others:

  • Do not leave the house if you are sick.
  • Do not share eating and drinking utensils with others.
  • Wear a mask, especially if other people are around.
  • Cover mouth and nose with a tissue when sneezing and coughing. If you don't have a tissue, cover your mouth and nose with your elbow crease.
  • Wash hands regularly.

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